Single reizen zijn reizen voor mensen die alleen op vakantie willen. Overigens hoeft iemand die alleen op vakantie gaat niet persé alleenstaand te zijn! Veel bestemmingen zijn altijd inclusief een 1-persoonskamer of een 2-persoonskamer voor alleengebruik · The FLT3 receptor is overexpressed on the majority of acute myeloid leukemia (AML) blasts. Mutations in FLT3 are the most common genetic alteration in AML, identified in approximately one third of newly diagnosed patients. FLT3 internal tandem duplication mutations (FLT3-ITD) are associated with increased relapse and inferior overall survival Der Weg ist das Ziel. 40 Kilometer Streckennetz, davon 20 Kilometer flowige Trails, die von leicht bis schwer klassifiziert sind. Der Trailpark Winterberg bietet vorwiegend familientaugliche Runden, aber auch Touren mit knackigen Anstiegen und Abfahrten für Ausdauernde
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Dortmund German: [ˈdɔʁtmʊnt] listen ; Westphalian Low German : Düörpm [ˈdyːœɐ̯pm̩] ; Latin : Tremonia is the third-largest city in North Single trail sauerland after Cologne and Düsseldorfand the eighth-largest city of Germanywith a population ofinhabitants as of It is the largest city by area and population of the RuhrGermany's largest urban area with some 5.
Dortmund is the second-largest city in the Low German dialect area after Hamburg. Founded around[3] Dortmund became an Imperial Free City. Throughout the 13th to 14th centuries, it was the "chief city" of the Rhine, Westphalia, and the Netherlands Circle of the Hanseatic League. During the Thirty Years' Warthe city was destroyed and decreased in significance until the onset of industrialization.
The city then became one of Germany's most important coal, steel and beer centres. Dortmund consequently was one of the most heavily bombed cities in Germany during World War II, single trail sauerland.
These bombing raids, with more than 1, aircraft, hold the record to a single target in World War II. The region has adapted since the collapse of its single trail sauerland steel and coal industries and shifted to high-technology biomedical technologymicro systems technologysingle trail sauerland, and also services. Dortmund was classified as a Node city in the Innovation Cities Index published by 2thinknow, single trail sauerland, [5] ranked among the twelve innovation cities in European Union [6] and is the most sustainable and digital city in Germany.
Dortmund is home to many cultural and educational institutions, including the Technical University of Dortmund and Dortmund University of Applied Sciences and Artssingle trail sauerland, International School of Management and single trail sauerland educational, cultural and administrative facilities with over 49, students, many museums, such as Museum OstwallMuseum of Art and Cultural HistoryGerman Football Museumas well as theatres and music venues like the Konzerthaus or the Opera House of Dortmund.
Nearly half the municipal territory consists of waterways, woodland, agriculture and green spaces with spacious parks such as Westfalenpark and Rombergpark. This stands in a stark contrast with nearly a hundred years of extensive coal mining and steel milling in the past, single trail sauerland. Borussia Dortmund is one of the most successful German football clubs. Dortmund was first mentioned in the Werden Abbeywhich was built between and The Latin entry reads: In Throtmanni liber homo Arnold viii den nob solvit.
German: In Throtmanni zahlt uns der freie Mann Arnold 8 Pfennige and English: In Throtmanni the free man Arnold pays us 8 pfennigs. Single trail sauerland respective use in the sources appears arbitrary and random.
In the course of time the name changed many times: trut muniaThortmanni, Trutmania, TrotmunniTremonia From the 13th century on, the Dortmunde appeared for the first time, single trail sauerland, but it was not until a few centuries later that it became generally accepted.
In the Middle Ageswhen the city had withstood the siege of knights under the leadership of the Archbishop of Cologneit chose as its motto a saying that is single trail sauerland upheld today by traditional societies: So fast as Düörpm.
High German : As firm as Dortmund. In the past, the city was called Dortmond in DutchTremonia in Spanish and Trémoigne in Old French. However, these exonyms have fallen into disuse and the city is now internationally known by its German name of Dortmund. The common abbreviation for the name of the city is "DTM", single trail sauerland, the IATA code for Dortmund Airport. The Sigiburg was a Saxon hillfort in the South of present-day Dortmund, overlooking the River Ruhr near its confluence with the River Lenne.
The ruins of the later Hohensyburg castle now stand on the site of the Sigiburg. The hillfort was raised ca, single trail sauerland. During the Saxon Warssingle trail sauerland, it was taken by the Franks under Charlemagne inretaken by the Saxons possibly under Widukind inand taken again and refortified by Charlemagne in Archaeological evidence suggests the Sigiburg site was also occupied in the Neolithic era.
The first time Dortmund was mentioned in official documents was around as Throtmanni — In throtmanni liber homo arnold[us] viii den[arios] nob[is] soluit [solvit]. After it was destroyed by a fire, the Holy Roman Emperor Frederick I Barbarossa had the town rebuilt in and resided there among other places for single trail sauerland years. In St. Mary's Church, Dortmund, and three years later in St.
Reinold's Church first mentioned, single trail sauerland. The combination of crossroad, market place, administrative centre — town hall, made Dortmund an important centre in Westphalia. It became an Single trail sauerland Free City and one of the first cities in Europe with an official Brewing right in Afterthe city appeared in writing as "Dorpmunde". In the years leading up tothe English King even borrowed money from well-heeled Dortmund merchant families Berswordt and Klepping, offering the regal crown as security.
Inthe Count of Mark joined forces with the Archbishop of Cologne and issued declarations of a feud against the town. Following a major siege lasting 18 months, peace negotiations took place and Dortmund emerged victorious. In the seat of the first Vehmic court German : Freistuhl was in Dortmund, in a square between two linden treesone of which was known as the Femelinde.
With the growing influence of Cologne during the 15th century, the seat was moved to Arnsberg in After Cologne was excluded after the Anglo-Hanseatic War —74Dortmund was made capital of the Rhine-Westphalian and Netherlands Circle.
This favors the founding of one of the oldest schools in Europe in - Stadtgymnasium Dortmund [ de ]. With the Reichsdeputationshauptschluss resolution inDortmund was added to the Principality of Nassau-Orange-Fuldawith as a result that it was no longer a free imperial city.
William V, Prince of Orange-Nassau did not want stolen areas and therefore let his son Prince Willem Frederik the later King William I of the Netherlands take possession of the city and the principality.
This prince held its entry on 30 Juneand as such the County of Dortmund then became part of the principality. On 12 Julymost of the Nassau principalities were deprived of their sovereign rights by means of the Rhine treaty.
In October of the same year, the County of Dortmund was occupied by French troops and was added to the Grand Duchy of Berg on 1 March It is the capital of single trail sauerland Ruhr department.
In Dortmund becomes capital of French satellite Ruhr department. The state mining authority of the Ruhr area was founded in and moved from Bochum to Dortmund. Within the Prussian Province of WestphaliaDortmund was a district seat within Regierungsbezirk Arnsberg untilwhen it became an urban district within the region. During the industrialisation of Prussia, Dortmund became a major centre for coal and steel. The town expanded into a city, with the population rising from 57, in toin Sprawling residential areas like the North, East, single trail sauerland, Union and Kreuz district sprang up in less than 10 years.
Insingle trail sauerland, Dortmund was one of the centres for resistance to the Kapp Putsch - a right military coup launched against the Social Democratic -led government. Radical workers formed a Red Army who fought the freikorps units involved in the coup.
On 11 Januarysingle trail sauerland, the Occupation of the Ruhr was carried out by the invasion of French and Belgian troops into the Ruhr. The French Prime Minister Raymond Poincaré was convinced that Germany failed to comply the demands of the Treaty of Versailles. On the morning of 31 Marchit came to the sad culmination of this French-German confrontation. Under Nazi Germanythe Old Synagoguewhich had opened inwas destroyed in With a capacity of 1, seats, it was one of the largest Jewish houses of worship in Germany.
Bombing targets of the Oil Campaign of World War II in Dortmund included Hoesch-Westfalenhütte AGthe " Hoesch -Benzin GmbH" synthetic oil plant, and the Zeche Hansa.
The Allied ground advance into Germany reached Dortmund in April The US 95th Infantry Division attacked the city on 12 April against a stubborn German defense. The division, assisted by close air support, advanced through the ruins in urban combat and completed its capture on 13 April Post-war, single trail sauerland, most of the ancient buildings were not restored, and large parts of the city area were completely rebuilt in the style of the s.
A few historic buildings as the main churches Reinoldikirche and Marienkirche were restored or rebuilt, and extensive parks and gardens were laid out. The simple but successful postwar rebuilding has resulted in a very mixed and unique cityscape. Dortmund was in the British zone of occupation of Germany, and became part of the new state Land of North Rhine-Westphalia in Single trail sauerland LWL-Industriemuseum was founded in Dortmund [25] has since adapted, with its century-long steel and coal industries having been shifted to high-technology areas, including biomedical technologymicro systems technologyand services.
This has led Dortmund to become a regional centre for hi-tech industry. In started a new era for the discrict Hörde in Dortmund, years of industrial history ended with the beginning of the Phoenix See. The development of the Phoenix See area was carried out by a subsidiary of the Stadtwerke AG. In the first cornerstone was laid on the Phoenix area. The work started with full single trail sauerland to manage the work with over 2.
On 1 Octoberthe largest and most highly anticipated milestone could be celebrated: the launch of the flooding of the Phoenix See. Since 9 Maythe fences disappeared and the Phoenix See has been completed. On 3 Novembermore than 20, people were evacuated after a 4,pound bomb from World War II was found. German authorities safely defused the bomb. The bomb single trail sauerland found after analysing old aerial photographs while searching for unexploded bombs dropped by Allied aircraft over Germany's industrial Ruhr region.
Dortmund is an independent city located in the east of the Ruhr area, one of the largest urban areas in Europe see also: megalopolissingle trail sauerland eleven independent cities and four districts with some 5.
The city limits of Dortmund itself are 87 km 54 single trail sauerland long and border twelve cities, two independent and ten kreisangehörig i. The following cities border Dortmund clockwise starting from north-east : BochumCastrop-Rauxelsingle trail sauerland, WaltropLünenKamenUnnasingle trail sauerland, HolzwickedeSchwerteHagenHerdecke and Witten. Historically speaking, Dortmund is a part of Westphalia which is situated in the Bundesland North Rhine-Westphalia.
Moreover, Dortmund is part of Westphalian Lowland and adjoins with the Ardey Hills in the south of the city to the Sauerland. The Ruhr forms the reservoir on the Hengsteysee next to the borough of Syburg in the south of Dortmund between the cities of Hagen and HerdeckeNorth Rhine-WestphaliaGermany. The Klusenberga hill that is part of the Ardey range, is located just north of the Hengsteysee and the highest point of Dortmund There is also a pumped-storage plant on this reservoir, named Koepchenwerk.
The lowest point can be found in the northern borough of Brechten at The Emscher is a small river and has its wellspring in Holzwickedeeast of the city of Dortmund, and flows west through Dortmund. Towns along the Emscher take in Dortmund, Castrop-RauxelHerneRecklinghausenGelsenkirchenEssenBottropOberhausen and Single trail sauerlandwhere it flows into the Rhine.
Dortmund comprises 62 single trail sauerland which in turn are grouped into twelve boroughs called Stadtbezirkeoften named after the most important neighbourhood. Three boroughs cover the area of the inner city Innenstadt-West City centre WestInnenstadt-Nord City centre NorthInnenstadt-Ost City centre East and the remaining nine boroughs make up the surrounding area Evingsingle trail sauerland, Scharnhorst, Brackel, AplerbeckHördeHombruch, Lütgendortmund, Huckarde, Mengede.
Each Stadtbezirk is assigned a Roman numeral and has a local governing body of nineteen members with limited authority.
Single-Trail im Sauerland
, time: 1:51Dortmund - Wikipedia
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